MODBUS协议支持传统的RS-232、RS-422、RS-485和以太网设备。许多工业设备，包括PLC，DCS，智能仪表等都在使用Modbus协议作为他们之间的通讯标准。
Modbus 协议是应用于电子控制器上的一种通用语言。通过此协议，控制器相互之间、控制器经由网络（例如以太网）和其它设备之间可以通信。Modbus 协议定义了一个控制器能认识使用的消息结构,而不管它们是经过何种网络进行通信的。它描述了一控制器请求访问其它设备的过程，如何回应来自其它设备的请求，以及怎样侦测错误并记录。它制定了消息域格局和内容的公共格式。(The MODBUS protocol supports traditional RS-232, RS-422, RS-485, and Ethernet devices. Many industrial devices, including PLC, DCS, and intelligent instruments, are using the Modbus protocol as a communication standard between them.
The Modbus protocol is a common language applied to the electronic controller. Through this protocol, controllers can communicate between each other and the controller via a network (such as Ethernet) and other devices. The Modbus protocol defines a controller that recognizes the message structure used, regardless of what network they communicate. It describes how a controller requests access to other devices, how to respond to requests from other devices, and how to detect errors and record. It formulates the public format of the message domain pattern and content.)